- Description
- Benefits
- Risks
- Additional information
- Research
Description
IGF-1 LR3 (Insulin-Like Growth Factor-1 Long R3) is a modified synthetic analogue of IGF-1, engineered for extended activity and reduced binding to IGF-binding proteins (IGFBPs) in research environments. It is widely studied for its role in cellular growth, protein synthesis, and metabolic signalling pathways.
In controlled laboratory settings, IGF-1 LR3 interacts with IGF-1 receptors (IGF-1R), activating intracellular pathways involved in cell proliferation, nutrient uptake, and anabolic signalling. Its structural modification allows for prolonged activity compared to native IGF-1, making it particularly relevant in extended-duration experimental models.
Across Ireland and Europe, IGF-1 LR3 is commonly included in research areas such as:
- Cellular growth and proliferation research
- Protein synthesis and anabolic signalling pathways
- IGF-1 receptor activation studies
- Metabolic regulation and nutrient signalling
This product is supplied as a high-purity research peptide, intended strictly for scientific and laboratory use.
Disclaimer: This product is strictly for research purposes only and is not for human consumption.
Technical Information – IGF-1 LR3
| Specification | Details |
|---|---|
| Product Name | IGF-1 LR3 |
| Compound Type | Synthetic IGF-1 analogue peptide |
| Functional Class | Growth factor peptide |
| Mechanism of Action | Activates IGF-1 receptors (IGF-1R) |
| Modification | Extended analogue with reduced IGFBP binding |
| Biological Targets | IGF-1 receptors, metabolic signalling pathways |
| Format | Lyophilised powder |
| Purity | Research-grade (high purity) |
| Storage | Refrigerated (2–8°C, protected from light) |
| Application | Laboratory research use only |
* Images for illustration purposes only
Further Refrences: PubChem Entry
Researched Benefits & Focus Areas – IGF-1 LR3
1. Cellular Growth & Proliferation Research
IGF-1 LR3 has been studied for:
- Activation of cell growth and division pathways
- Stimulation of cellular development in experimental models
- Investigation of growth factor signalling systems
Reference basis: Derived from molecular biology and endocrinology research examining IGF-1 receptor signalling and cellular proliferation pathways.
2. Protein Synthesis & Anabolic Pathways
Research has explored:
- Enhanced protein synthesis mechanisms
- Activation of anabolic signalling cascades (e.g. PI3K/Akt pathways)
- Influence on cellular nutrient utilisation and growth processes
Reference basis: Based on biochemical studies investigating IGF-1 pathway activation and protein synthesis regulation.
3. Extended Activity & IGFBP Interaction
IGF-1 LR3 is designed to:
- Reduce interaction with IGF-binding proteins (IGFBPs)
- Provide prolonged receptor activation in research models
- Support extended-duration experimental studies
Reference basis: Supported by pharmacological research into IGF-1 analogue modifications and peptide stability enhancement.
4. Metabolic & Nutrient Signalling
- Studied for its role in glucose uptake and metabolic pathways
- Explored in energy utilisation and cellular efficiency models
- Investigated for interaction with insulin-like signalling systems
Reference basis: Derived from research into IGF-1 signalling and metabolic regulation mechanisms.
Disclaimer: These are research-based findings only. This product is not intended for human use or consumption.
Researched Risks & Considerations – IGF-1 LR3
1. Broad Cellular Proliferation Effects
- May stimulate cell growth across multiple tissues
- Potential for uncontrolled proliferation in experimental models
Reference basis: Based on research into IGF-1 signalling and its role in regulating cell growth and division.
2. Metabolic Pathway Influence
- May affect glucose metabolism and insulin signalling
- Potential for system-wide metabolic changes in models
Reference basis: Derived from studies examining IGF-1 and insulin pathway interactions.
3. Off-Target Biological Activity
- Interaction with multiple cell types and receptors
- Potential for non-specific signalling effects
Reference basis: Based on research into IGF-1 receptor distribution and systemic signalling pathways.
4. Limited Long-Term Data
- Lack of long-term validated research
- Primarily studied in controlled laboratory environments
Reference basis: Reflects the current stage of IGF-1 analogue research.
Disclaimer: These risks are based on available research data only. This product is strictly a research peptide and not for human consumption.
Additional information
| Weight | 23 kg |
|---|---|
| Dimensions | 12 × 23 × 56 cm |
| Quantity | 1 Vial, 1 Kit (10 Vials) |
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