- Description
- Benefits
- Risks
- Additional information
- Research
Description
IGF-1 LR3 (Insulin-Like Growth Factor-1 Long R3) is a synthetic analogue of IGF-1, modified to provide extended biological activity and reduced binding to IGF-binding proteins (IGFBPs) in research models. It is widely studied in laboratory environments for its role in cellular growth, proliferation, and metabolic signalling pathways.
In controlled experimental settings, IGF-1 LR3 interacts with IGF-1 receptors (IGF-1R), activating intracellular pathways involved in cell division, protein synthesis, and nutrient utilisation. Its extended structure allows for prolonged activity compared to native IGF-1, making it a key compound in advanced research.
Across Ireland and Europe, IGF-1 LR3 is commonly explored in studies involving:
- Cellular growth and proliferation pathways
- Protein synthesis and anabolic signalling research
- IGF-1 receptor (IGF-1R) activation
- Metabolic regulation and nutrient signalling
This product is supplied as a high-purity research peptide, intended strictly for scientific and laboratory use.
Disclaimer: This product is strictly for research purposes only and is not for human consumption.
Technical Information – IGF-1 LR3
| Specification | Details |
|---|---|
| Product Name | IGF-1 LR3 |
| Compound Type | Synthetic IGF-1 analogue peptide |
| Functional Class | Growth factor peptide |
| Mechanism of Action | Activates IGF-1 receptors (IGF-1R) |
| Modification | Extended analogue with reduced IGFBP binding |
| Biological Targets | IGF-1 receptors, metabolic signalling pathways |
| Format | Lyophilised powder |
| Purity | Research-grade (high purity) |
| Storage | Refrigerated (2–8°C, protected from light) |
| Application | Laboratory research use only |
* Images for illustration purposes only
Further Refrences: PubChem Entry
Researched Benefits & Focus Areas – IGF-1 LR3
1. Cellular Growth & Proliferation Research
IGF-1 LR3 has been studied for:
- Stimulation of cell division and proliferation pathways
- Activation of growth-related intracellular signalling
- Research into cellular development and expansion models
Reference basis: Derived from molecular biology and endocrinology research examining IGF-1 receptor signalling and cellular growth pathways.
2. Protein Synthesis & Anabolic Signalling
Research has explored:
- Enhanced protein synthesis in experimental models
- Activation of anabolic signalling cascades (e.g. PI3K/Akt pathways)
- Influence on cellular nutrient utilisation
Reference basis: Based on biochemical studies investigating IGF-1 pathway activation and protein synthesis mechanisms.
3. Extended Activity & Reduced Binding
IGF-1 LR3 is modified to:
- Reduce binding to IGF-binding proteins (IGFBPs)
- Extend biological activity in research environments
- Enable longer-lasting receptor interaction
Reference basis: Supported by pharmacological research on IGF-1 analogues and peptide modification strategies.
4. Metabolic & Nutrient Signalling Research
- Studied for its role in glucose and nutrient uptake pathways
- Explored in metabolic regulation models
- Investigated for interaction with insulin-like signalling systems
Reference basis: Derived from research into IGF-1 signalling and metabolic pathway regulation.
Disclaimer: These are research-based findings only. This product is not intended for human use or consumption.
Researched Risks & Considerations – IGF-1 LR3
1. Uncontrolled Cellular Proliferation
- May stimulate cell growth pathways broadly
- Potential for unregulated proliferation in experimental models
Reference basis: Based on research into IGF-1 signalling and its role in cell growth and proliferation.
2. Metabolic System Impact
- May influence glucose metabolism and insulin-related pathways
- Potential for system-wide metabolic effects
Reference basis: Derived from studies examining IGF-1 and insulin signalling interactions.
3. Off-Target Biological Effects
- Broad interaction across multiple cell types
- Potential for non-specific signalling activation
Reference basis: Based on research into IGF-1 receptor distribution across tissues.
4. Limited Long-Term Research
- Lack of long-term safety data
- Primarily studied in controlled laboratory environments
Reference basis: Reflects the current stage of IGF-1 analogue research.
Disclaimer: These risks are based on available research data only. This product is strictly a research peptide and not for human consumption.
Additional information
| Weight | 23 kg |
|---|---|
| Dimensions | 12 × 23 × 56 cm |
| Quantity | 1 Vial, 1 Kit (10 Vials) |
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